The GUTS Of The Pressure Theory

Here's the gist of it. After a person who does not have diabetes eats, he or she experiences a surge of insulin. That insulin stops the liver from releasing glucogen and turns it into create-glycogen-mode. The insulin turns on muscle cells to accept glucogen. If a person has diabetes, there is no surge. Some insulin comes out, but not enough to handle the bounty of glucogen coming from the food, and not enough to turn the liver off. The glucogen that the liver continues to produce compounds matters. Soon there is more glucogen in the system than the system can handle, even though insulin continues to be produced, slowly, by the pancreas. So the problem is, according to my theory, that the diabetic lacks an insulin surge.

The most likely culprit for the lack of insulin surge is a decreased blood flow to the pancreas. It just so happens that the same arteries that feed the first part of the small intestine (the duodenum) also feed the pancreas. They are "co" arteries: the superior and inferior pancreaticoduodenal arteries. It is my theory that branches of these arteries become pinched when fat or baby push on the stomach, yanking and torquing the duodenum. If that pressure is relieved by losing weight and keeping it off, by delivering the baby, or by surgery (Dr. Roubino showed that surgery resolves diabetes, though he does not propose pressure as culprit), then blood flows again, the insulin surge resumes, and diabetes is relieved.

If you read the entire essay, you will see references to articles and websites, references to illustrations. I propose experiments that will confirm or deny the theory. I also defend the theory against other theories.